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I'm a proud christian. I Love God's creations, especially if they're cute and fluffy. I like making food. I also like romantic posts. I'm currently studying for the MCAT.
So you could find anything relating to the things i've just mentioned in my blog.

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I try to follow everyone back but if they post something that's NSFW or anything else that i think is inappropriate for my Christian walk, I'll have to unfollow. Nothing against them, I'm just trying to keep myself away from any possible temptations. Thanks for understanding. :)
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diamants-bruts:

either grapes #delicious #candies #Raccoon #cute #greedy

diamants-bruts:

either grapes
#delicious #candies #Raccoon #cute #greedy

Thursday, April 10, 2014
psychofactz:

More Facts on Psychofacts :)

That what i keep telling my mother but she won’t believe me…

psychofactz:

More Facts on Psychofacts :)

That what i keep telling my mother but she won’t believe me…

lizzysouth:

Me when I overestimate how much someone likes me

lizzysouth:

Me when I overestimate how much someone likes me

Wednesday, April 2, 2014
"Liebe ist das, was dich lächeln lässt, wenn du müde bist."
Paulo Coelho (via egal-schillerwardichter)
diamants-bruts:

headquarters #fox #water #crystalline #animal #nature

diamants-bruts:

headquarters
#fox #water #crystalline #animal #nature

Once Upon A Time

prideslimy:

escaped—words:

Once upon a time I told you I’d love you forever
on a day where I was too young and dumb
and iocent.
Five years later I’m falling asleep
in someone else’s arms,
and am in love with someone
who is not you.
But I swear,
everything I said was true.

You live in the corner of my mind,
in a place crammed in the corner
far, far away
filled with first kisses
and summer days
and iocence
and broken hearts.

I did not lie to you.
That is where I will love you
forever.

nice poem

Tuesday, March 18, 2014
Friday, March 14, 2014

thelifeofapremed:

Transcription of DNA into RNA, enzymatic reactions, RNA, RNA degradation

  • Transcription
    1. Initiation: promoter recognition, closed complex, open complex.
      • Promoter:
        • Prokaryotic: ←upstream, -35 region, Pribnow box, transcription start site (TSS, +1), downstream→
        • Eukaryotic: ←upstream, several upstream elements, TATA box, initiator element containing TSS (+1), downstream→
        • The high A-T composition in promoters facilitate unwinding of DNA.
        • Template strand = antisense strand = (-) strand = noncoding strand = the DNA strand that serves as the template for transcription.
        • Nontemplate strand = sense strand = (+) strand = coding strand = the DNA strand having the same sequence as the transcribed RNA.
      • Binding to promoter:
        • Prokaryotic:
          • holoenzyme = core enzyme (polymerase activity) + σ-subunit (promoter and strand specificity).
          • binding first forms the closed complex, and then DNA opens up, forms the open complex.
        • Eukaryotic:
          • A whole bunch of transcription factors (TFs) involved in promoter recognition, binding, and openning up DNA.
          • TBP = Tata binding protein. TAF = TBP associated factor.
          • Phosphorylation of Pol II C-terminal domain (CTD) opens DNA up, forms the open complex.
        • Polymerase must transcribe using the correct template strand. The σ-factor (prokaryotes) and TFs (eukaryotes) tell the RNA polymerase to bind the coding strand, while using the template strand as the template.
    2. Elongation:
      • Polymerases:
        • Prokaryotes have just one.
        • Eukaryotes have three:
          • 1. RNA Pol I: makes rRNA (except the small 5S rRNA that resembles a tRNA in size).
          • 2. RNA Pol II: makes mRNA.
          • 3. RNA Pol III: makes tRNA (and 5S rRNA).
      • Incorporation of NTPs.
      • Prokaryotes lose σ-subunit. Eukaryotes lose TFs.
      • Topoisomerases relaxing supercoils ahead and behind the polymerase.
      • Transcription-coupled repair: RNA Pol II encounters DNA damage, backs up, TFIIH comes along, recruits repair enzymes. Defective TFIIH → faulty transcription-coupled repair → Xeroderma pigmentosum and Cockayne syndrome (skin sensitive to sunlight radiation in both diseases).
    3. Termination
      • Prokaryotic:
        • Intrinsic termination: GC hairpin (stalls polymerase) followed by poly U (slips off).
        • Rho-dependent termination: ρ protein catches up to polymerase when it stalls at the hairpin, and bumps it off.
      • Eukaryotic:
        • Termination consensus sequence reached (AAUAAA).
        • Polymerase released somewhere further downstream to the consensus sequence.
  • RNA
    • 1. RNA = ribonucleic acid, has 2’-OH.
    • 2. rRNA = ribosomal RNA
      • Most abundant (r for rampant).
      • Catalyzes peptide bond formation in the ribosome.
    • 3. mRNA = messenger RNA
      • Longest (m for massive).
      • Contains sequence of codons for translation.
      • RNA splicing
        • pre-mRNA need to be processed.
        • Introns = interfering sequences, cut out.
        • Exons = spliced together.
        • RNA splicing proceeds via a lariat intermediate, by the action of the spliceosome (snRNPs), introns released in lariat form.
        • Some RNA can self splice.
    • 4. tRNA = transfer RNA
      • Smallest (t for tiny).
      • Contains anticodon.
      • Shuttles the correct amino acid to the correct codon during translation.
    • 5. snRNPs (snurps) = RNA + protein, involved in RNA splicing.
  • RNA degradation
    • RNases degrade RNA.
    • Post-transcriptional modifications protect RNA from degradation (5’ cap and polyA tail)
    • 2’-O-methylation prevents that position from attacking the RNA backbone.
 
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